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Registered Nurse, Stem Cell Night

City of Hope Chicago · Zion, IL · Full time

Posted Jul 28, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

How do you keep up strict infection control on a night shift when you are tired and the unit is quiet?

What they are checking: Whether safety habits hold up when no one is watching and fatigue sets in.

Tell me about a time a patient could not sleep because of fear or pain. How did you help?

What they are checking: Comfort and presence for patients facing long, frightening nights in the hospital.

Tell me about a time you made a mistake or near miss on a shift. What did you do?

What they are checking: Honesty and accountability, which matter greatly with high-risk transplant medications.

What draws you to stem cell transplant nursing, and how do you see yourself handling permanent nights?

What they are checking: Real motivation for this specialty and realistic plans for sustaining a night schedule.

What would you do

How do you decide when a change in a transplant patient is worth waking the on-call provider?

What they are checking: Judgment and clear communication with physicians who are not in the building overnight.

How do you guide a patient care technician on nights when you have a heavy assignment?

What they are checking: Delegation and teamwork that keep a night shift running safely.

About the work

It is 2 a.m. and your neutropenic transplant patient spikes a fever of 101. Walk me through the next hour.

What they are checking: Treating neutropenic fever as an emergency, with cultures and antibiotics started fast even on nights.

Your patient's platelets are very low and they now have a nosebleed that will not stop. What do you do?

What they are checking: Bleeding precautions and escalation for severely thrombocytopenic patients.

What signs of graft-versus-host disease or veno-occlusive disease would you watch for on night rounds?

What they are checking: Specific transplant knowledge that lets them catch serious complications early.

How do you give a handoff to the day nurse so that nothing important is lost?

What they are checking: Clear, complete shift report that protects continuity of care for complex patients.

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The full job description

As published by City of Hope Chicago.

Registered Nurse, Stem Cell Night About City of Hope , City of Hope's mission is to make hope a reality for all touched by cancer and diabetes. Founded in 1913, City of Hope has grown into one of the largest and most advanced cancer research and treatment organizations in the U.S., and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center that is ranked top 5 in the nation for cancer care by U.S. News & World Report at its core, City of Hope’s uniquely integrated model spans cancer care, research and development, academics and training, and a broad philanthropy program that powers its work. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and cancer treatment centers and outpatient facilities in the Atlanta, Chicago and Phoenix areas. **$20,000 Sign on Bonus eligible** The successful candidate: • Assesses, plans, implements, evaluates and documents the care of hematology/oncology, stem cell transplant & ambulatory care patients. • Assists with special procedures. • Directs the care delivered by patient care technicians and other members of the healthcare team. • Demonstrate basic knowledge of procedures, treatments, and equipment • Demonstrate basic knowledge and care of complex medical hematology/oncology, stem cell transplant or critical care patients. • Caring for patients with complex needs including hemodynamically compromised and mechanically ventilated patients • Initiating and maintain complex IV therapy, including thrombolytic administration, vasoactive medications, central IV catheters, dialysis catheters & arterial lines • Safe use of less invasive, life supporting modalities i.e. BiPAP, ETCO2, arterial pressure-based CO/CI & SVO2 monitor, core temperature monitors • Caring for autologous & allogeneic transplant patients, stem cell collection, & ECP patients • Attend In-House Code Blue and Rapid Response Calls, as required • Recognize cardiac arrhythmias and notify physician • Must be able to work 7p-7a, 3 12's Qualifications Your qualifications should include: • Critical Care/telemetry experience or telemetry competency within 6 months of hire • Critical Care experience or completes in-house critical care courses 12 months of hire • Graduate of NLNAC or CCNE School of Nursing • State of Illinois Registered Nurse License. • BLS certification upon hire and maintained in position. • ACLS certification upon hire or obtained within 90 days of hire and maintained in position. • ONS Chemotherapy/Biotherapy certified within 6 months for experienced RN - 12 months for new RN’s • Oncology Certification through ONCC when eligible or 6 oncology CE every year (18 oncology CE total every 3 years) for the Oncology Commission Cancer cycle. Telemetry - Recognize cardiac arrhythmias and institute appropriate interventions City of Hope is an equal opportunity employer. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

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