Registered Nurse, Apheresis
Posted Sep 21, 2026 · We last checked this listing on Oct 6, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
Tell me about a time a procedure did not go as planned. How did you respond?
What they are checking: Calm problem solving with technically complex equipment and patients.
What experience do you have with apheresis machines, dialysis or similar extracorporeal procedures?
What they are checking: Relevant technical background for learning this specialized procedure safely.
Tell me about a time you had to learn a complex new skill quickly.
What they are checking: Learning ability for a highly specialized role with a steep learning curve.
What would you do
Your patient's blood pressure drops during the procedure. What do you do?
What they are checking: Fast response to hemodynamic changes common during apheresis.
How do you work with the stem cell transplant team and lab to schedule and track collections?
What they are checking: Coordination skills that keep transplant timelines on track.
About the work
Walk me through how you prepare a stem cell donor for a peripheral blood stem cell collection.
What they are checking: Knowledge of donor screening, mobilization and preparation for a safe collection.
During apheresis your patient complains of tingling around the mouth and fingers. What is happening and what do you do?
What they are checking: Recognition of citrate toxicity and quick, correct management.
How do you manage the central line or access used for apheresis to prevent infection or clotting?
What they are checking: Vascular access care skills that protect patients undergoing repeated procedures.
How do you explain plasmapheresis to a patient who is nervous about the machine?
What they are checking: Clear patient teaching that eases fear and supports informed consent.
How do you make sure the collected product is labeled and handled correctly?
What they are checking: Chain of custody and labeling discipline that protect a transplant patient's cells.
Practice this interview out loud.
Offer builds a real interview for this exact role at City of Hope Chicago from your resume and this job description, asks the questions one at a time, and tells you what landed. The first one is free.
Practice this out loudThe full job description
As published by City of Hope Chicago.