Registered Nurse, Infusion
Posted Sep 24, 2026 · We last checked this listing on Oct 6, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
Tell me about a busy infusion day when several patients needed you at once. How did you decide what to do first?
What they are checking: Prioritization in a high-volume clinic where delays affect many patients and their treatment timing.
Tell me about a time you taught a patient something that helped them avoid a complication at home.
What they are checking: Patient teaching that sticks and reduces avoidable ER visits between treatments.
Do you hold chemo-biotherapy or OCN certification, and how have you kept your infusion skills current?
What they are checking: Formal oncology training and commitment to staying current in a fast-changing specialty.
What would you do
How do you guide the patient care partners working with you during an infusion shift?
What they are checking: Delegation and leadership, since the posting says the RN directly guides care partners.
A patient's labs come back with a low neutrophil count right before treatment. What do you do?
What they are checking: Whether they hold treatment and contact the provider rather than proceeding on schedule.
About the work
Walk me through how you verify a chemotherapy order before you hang it.
What they are checking: Rigorous independent double-check habits for high-risk drugs where an error can be fatal.
Your patient develops back pain, flushing and shortness of breath a few minutes into a monoclonal antibody infusion. What do you do?
What they are checking: Fast recognition of a hypersensitivity reaction and command of the steps to stop and treat it.
How do you manage a vesicant infusion through a port, and what would make you stop?
What they are checking: Knowledge of extravasation risk and the safety checks that protect patients from tissue damage.
You care for infusion patients of all ages. How does your approach change for an older adult versus a younger adult?
What they are checking: Age-appropriate assessment and teaching across the wide patient range the role serves.
How do you handle chemotherapy safely to protect yourself and others from exposure?
What they are checking: Knowledge of PPE and safe handling standards for hazardous drugs.
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Practice this out loudThe full job description
As published by City of Hope Chicago.