Jobs › City of Hope Chicago

Registered Nurse, Stem Cell/ICU

City of Hope Chicago · Zion, IL · Full time

Posted Jul 22, 2026 · We last checked this listing on Oct 6, 2026

Apply at City of Hope Chicago

Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time a patient on your unit deteriorated quickly. What did you do?

What they are checking: Calm, organized response to a rapid decline in high-acuity hematology or oncology patients.

Tell me about a time you supported a patient through a long, isolating hospital stay.

What they are checking: Emotional support skills for transplant patients who are often hospitalized for weeks.

What hematology, oncology, BMT or ICU background do you bring, and where would you need more training?

What they are checking: Honest self-assessment of readiness for a mixed stem cell and ICU assignment.

What would you do

This role covers stem cell transplant, ICU-level care and ambulatory patients. How would you shift gears between them?

What they are checking: Flexibility across acuity levels and the ability to change focus without missing details.

How do you direct a patient care technician when isolation precautions and timing are critical?

What they are checking: Delegation that keeps strict protocols intact when others are helping with care.

About the work

Walk me through how you would monitor a patient in the first weeks after an allogeneic stem cell transplant.

What they are checking: Knowledge of transplant timelines, engraftment and the infection and bleeding risks that follow.

Your post-transplant patient develops a new rash, diarrhea and rising bilirubin. What are you thinking and what do you do?

What they are checking: Recognition of possible graft-versus-host disease and prompt escalation to the transplant team.

How do you protect a neutropenic patient from infection during a busy shift?

What they are checking: Strict infection prevention habits for profoundly immunosuppressed patients.

How do you safely administer blood products to a transplant patient, and what reactions do you watch for?

What they are checking: Knowledge of irradiated products, transfusion reactions and close monitoring in this group.

A patient is developing signs of tumor lysis syndrome. What labs and signs concern you and what do you do?

What they are checking: Recognition of a serious oncologic emergency and knowing what to report quickly.

Practice this interview out loud.

Offer builds a real interview for this exact role at City of Hope Chicago from your resume and this job description, asks the questions one at a time, and tells you what landed. The first one is free.

Practice this out loud

The full job description

As published by City of Hope Chicago.

Registered Nurse, Stem Cell/ICU About City of Hope , City of Hope's mission is to make hope a reality for all touched by cancer and diabetes. Founded in 1913, City of Hope has grown into one of the largest and most advanced cancer research and treatment organizations in the U.S., and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center that is ranked top 5 in the nation for cancer care by U.S. News & World Report at its core, City of Hope’s uniquely integrated model spans cancer care, research and development, academics and training, and a broad philanthropy program that powers its work. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and cancer treatment centers and outpatient facilities in the Atlanta, Chicago and Phoenix areas. The successful candidate: • Assesses, plans, implements, evaluates and documents the care of hematology/oncology, stem cell transplant & ambulatory care patients. • Assists with special procedures. • Directs the care delivered by patient care technicians and other members of the healthcare team. • Demonstrate basic knowledge of procedures, treatments, and equipment • Demonstrate basic knowledge and care of complex medical hematology/oncology, stem cell transplant or critical care patients. • Caring for patients with complex needs including hemodynamically compromised and mechanically ventilated patients • Initiating and maintain complex IV therapy, including thrombolytic administration, vasoactive medications, central IV catheters, dialysis catheters & arterial lines • Safe use of less invasive, life supporting modalities i.e. BiPAP, ETCO2, arterial pressure-based CO/CI & SVO2 monitor, core temperature monitors • Caring for autologous & allogeneic transplant patients, stem cell collection, & ECP patients • Attend In-House Code Blue and Rapid Response Calls, as required • Recognize cardiac arrhythmias and notify physician • Must be able to work 7a-7p, 3 12's Qualifications Your qualifications should include: • Critical Care/telemetry experience or telemetry competency within 6 months of hire • Critical Care experience or completes in-house critical care courses 12 months of hire • Graduate of NLNAC or CCNE School of Nursing • Oncology Certification through ONCC when eligible or 6 oncology CE every year (18 oncology CE total every 3 years) for the Oncology Commission Cancer cycle. Telemetry - Recognize cardiac arrhythmias and institute appropriate interventions • BLS certification upon hire and maintained in position. • ACLS certification upon hire and maintained in position. • ONS Chemotherapy/Biotherapy certified within 6 months for experienced RN - 12 months for new RN’s • National Institutes of Health Stroke Scale (NIHSS)certification within 6 months of hire and maintained in position. City of Hope is an equal opportunity employer. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

Apply at City of Hope Chicago