Registered Nurse, ICU Night *$20,000 Sign on Bonus*
Posted Aug 4, 2026 · We last checked this listing on Oct 6, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
Tell me about a time you noticed a subtle change in a patient that turned out to be serious.
What they are checking: Sharp assessment skills and the confidence to act on a gut sense with clear data.
Tell me about a time you supported a family when their loved one was dying in the ICU.
What they are checking: Compassion and skill in end-of-life care, which is common in an oncology ICU.
How do you stay sharp and safe on a run of night shifts?
What they are checking: Self-care habits and fatigue awareness that protect patients on a long-term night schedule.
How many years of ICU experience do you have, and what drips and devices are you most comfortable managing?
What they are checking: Readiness to handle a full ICU assignment independently with adolescent and adult patients.
What would you do
On nights there are fewer physicians in the building. How do you decide when to call and how do you present the situation?
What they are checking: Clear, concise communication like SBAR and good judgment about when a problem cannot wait.
How do you direct a patient care technician on your shift while managing two unstable patients?
What they are checking: Delegation and prioritization skills, since the posting expects the RN to guide care partners.
About the work
It is 3 a.m. and your septic patient's blood pressure keeps dropping despite fluids. Walk me through what you do and who you call.
What they are checking: Recognition of septic shock, escalation at night, and comfort with vasopressors and protocols.
How does caring for a critically ill cancer patient differ from caring for a general ICU patient?
What they are checking: Awareness of oncology issues like neutropenia, tumor lysis and bleeding risk in critical care.
Walk me through how you assist with a special procedure at the bedside, like a central line placement.
What they are checking: Knowledge of sterile technique, timeouts and patient monitoring during bedside procedures.
Your patient on a ventilator suddenly desaturates and the alarm is going off. What do you check first?
What they are checking: A fast, ordered response to vent emergencies, such as using DOPE to find the cause.
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Practice this out loudThe full job description
As published by City of Hope Chicago.