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Registered Nurse, ER Nights

City of Hope Chicago · Zion, IL · Full time

Posted Aug 26, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time a patient or family member got angry in the ER. How did you handle it?

What they are checking: De-escalation skills and calm communication in a stressful environment.

Tell me about a time you noticed a patient getting worse while they were waiting to be seen.

What they are checking: Attention to patients in the waiting area and willingness to escalate early.

How do you stay alert and safe working ER nights?

What they are checking: Practical habits for managing fatigue on a long-term night schedule.

What ER experience and certifications like ACLS, PALS or TNCC do you bring?

What they are checking: Readiness to work independently in an emergency department at night.

What would you do

Three patients walk in at once: chest pain, a cancer patient with fever, and a deep cut. How do you triage them?

What they are checking: Triage judgment, including treating fever in a chemo patient as potentially life-threatening.

How do you communicate with a physician when you disagree about a patient's plan?

What they are checking: Whether they can advocate for a patient with a physician clearly and respectfully, without backing down or picking a fight.

About the work

How is caring for a cancer patient in the ER different from a typical ER patient?

What they are checking: Awareness of oncologic emergencies like neutropenic sepsis, spinal cord compression and hypercalcemia.

Your patient becomes unresponsive while you are with them. Walk me through what you do.

What they are checking: Fast, organized emergency response, including starting a code and calling for help.

How do you keep track of several patients' meds, labs and reassessments on a busy night shift?

What they are checking: Organization and time management that keep patients safe during a fast-paced shift.

A patient with a port comes in with fever. What do you do with the port?

What they are checking: Knowledge of accessing ports and drawing cultures in suspected line infections.

Practice this interview out loud.

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The full job description

As published by City of Hope Chicago.

Registered Nurse, ER Nights About City of Hope , City of Hope's mission is to make hope a reality for all touched by cancer and diabetes. Founded in 1913, City of Hope has grown into one of the largest and most advanced cancer research and treatment organizations in the U.S., and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center that is ranked top 5 in the nation for cancer care by U.S. News & World Report at its core, City of Hope’s uniquely integrated model spans cancer care, research and development, academics and training, and a broad philanthropy program that powers its work. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and cancer treatment centers and outpatient facilities in the Atlanta, Chicago and Phoenix areas. The successful candidate: • Provide direct, compassionate care to patients in a fast-paced emergency setting, including triaging, assessing, and prioritizing care needs. • Perform clinical assessments, administer medications, monitor vital signs, and provide treatment in alignment with department protocols and patient needs. • Manage complex patient situations, utilizing critical thinking and problem-solving skills. • Respond promptly to emergency situations and assist in life-saving procedures such as CPR, and other emergency protocols. • Ability to work well under pressure and in fast-paced environments. • Demonstrates competence in patient triage and medical screening exams using the established protocols • Demonstrates knowledge and use of Vasoactive medications • Ability to read and operate cardiac monitor, recognize normal/abnormal rhythms, and institute appropriate interventions • Quickly identifies signs and symptoms of emergent and/or life-threatening conditions and demonstrates skills to follow appropriate protocols, policies, and procedures to ensure goal times are met • Attend In-House Code Blue and Rapid Response Calls, as required • Must be able to work 3 12's, 7p-7a Qualifications • 1 year emergency or critical care experience • Graduate of NLNAC or CCNE school of Nursing • State of Illinois Registered Nurse License. • BLS certification upon hire and maintained in position. • ACLS upon hire and maintained in position • PALS certification upon hire or obtained within 6 months of hire and maintained in position. • National Institutes of Health Stroke Scale (NIHSS)certification within 6 months of hire and maintained in position. • Oncology Certification through ONCC when eligible or 6 oncology CE every year (18 oncology CE total every 3 years) for the Oncology Commission Cancer cycle. City of Hope is an equal opportunity employer. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. Please note : City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews. • Apply only through our official website or trusted partner platforms. • City of Hope will never request payment or fees at any stage of the hiring process. • We will not request sensitive personal or financial information prior to the acceptance of a formal offer. • All communications will come from official @coh.org email addresses. • Interviews are conducted only through approved, professional channels. • Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices. • If you receive any suspicious communication, please report it to careers@coh.org .

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