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Lead Medical Lab Scientist

Southern Illinois Healthcare · Harrisburg, IL · $31.80–$49.29 an hour · Full time

Posted Oct 2, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time you had to correct a coworker's work. How did you approach it?

What they are checking: Whether they can lead peers with respect while keeping quality standards firm.

How do you share lab initiatives with staff who don't see why a change matters?

What they are checking: Whether they can explain changes and get buy-in, which the posting lists as part of the lead role.

Tell me about a time you solved a tricky specimen or instrument problem.

What they are checking: Whether they have the technical depth to fix problems that others on the team bring to them.

What would you do

As lead at a smaller hospital like Harrisburg, how would you cover all departments when one person calls off?

What they are checking: Whether they can reassign work and keep testing moving with a lean staff in a rural lab.

A sample arrives hemolyzed from the ER and the doctor needs a potassium now. What do you do?

What they are checking: Whether they protect result accuracy while communicating urgently with the ER about recollection.

About the work

Walk me through how you'd handle a critical value on a weekend when you can't reach the ordering provider.

What they are checking: Whether they know critical value escalation rules and document every attempt to notify.

Your QC fails on a chemistry analyzer in the middle of a busy morning. What happens next?

What they are checking: Whether they stop patient testing, troubleshoot and look back at results instead of pushing through.

How would you train a new tech on high complexity testing and confirm they're competent?

What they are checking: Whether they understand competency assessment and do not let staff test alone too soon.

How do you prepare for an inspection, and what are the areas you'd check first?

What they are checking: Whether they understand regulatory readiness and keep documentation inspection ready all year.

How do you handle send-out testing so nothing gets lost between the hospital and the reference lab?

What they are checking: Whether they have a tracking process for send-outs so delays and lost samples are caught.

Practice this interview out loud.

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The full job description

As published by Southern Illinois Healthcare.

Current SIH employees need to apply for positions through our internal job portal. Log in to Workday to apply through the Jobs Hub. Location: Harrisburg, IL Shift: Days Time Type: Full-Time Facility/Clinic Name: Harrisburg Medical Center Position Summary • Responsible for collecting, processing, and performing testing of patient specimens. Principal Accountabilities • Standards of Performance: Respect, Integrity, Compassion, Collaboration, Stewardship, Accountability, Quality Education • Bachelor’s degree (or Associates Degree for grandfathered personnel) Licenses and Certification • MLS (ASCP) or equivalent certification required Experience and Skills • 5+ years of experience in a clinical laboratory. • Leadership and technical expertise. Physical Activities • Intermittent hand manipulation required • Intermittent lifting and carrying of 50 pounds Role Specific Responsibilities • Supports and communicates Laboratory initiatives and philosophies. • Perform routine waived, moderately, and high complex testing. • Collects, Processes and Receives specimens (including blood, urine, fecal, body fluid) to be analyzed in all departments of the clinical laboratory (listed above). • Evaluates and solves problems related to collection and processing of biological specimens of analysis of all age ranges. • Prepare samples for testing and send out to reference laboratories • Maintain laboratory equipment and stock supplies. • Performs complex laboratory procedures; recognizes deviation from expected results; analyzes and corrects problems using scientific principles under direct supervision per CLIA requirements. • Analyzes quality control data, makes judgments concerning results and takes appropriate action to maintain accuracy and precision. • Assist in troubleshooting and instrument maintenance. • Participate in training programs. • Participate in accreditation activities. • Participate in comparison studies and validation of new equipment. • Assist in troubleshooting and resolving instrument failures. • Oversee quality control programs and proficiency testing. • Work closely with supervisors on laboratory operations. • Assist with regulatory compliance and inspections. • Serve as a mentor to fellow coworkers. • Provide continuing education for staff. • Assist in writing and revising laboratory procedures. • Supervise daily operations and serve as a key operator for testing platforms. • Lead troubleshooting and quality improvement initiatives. • Ensure adherence to CAP, CLIA, and hospital regulations. • Collaborate with leadership on new testing implementation. • Assist in maintaining accreditation and compliance documentation. • Serve as a subject matter expert in one or more lab disciplines. • Complete department-required continuing education annually Compensation (Commensurate with experience): $31.8 To $49.29 To access our Benefits Guide/Plan Information, please click the link below: http://www.sih.net/careers/benefits

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