Jobs › Tempus AI

Senior Product Manager

Tempus AI · Chicago, IL · Full time

Posted Jun 3, 2026 · We last checked this listing on Oct 6, 2026

Apply at Tempus AI

Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a product you took through FDA clearance. What was the hardest part?

What they are checking: First-hand regulatory experience and how they handled setbacks along the way.

Tell me about a time you had to cut scope to hit a regulatory or commercial deadline.

What they are checking: Judgment about what can safely wait and how they communicate tradeoffs.

What would you do

How would you decide which ECG-AI algorithm to build next?

What they are checking: Whether they weigh clinical need, data availability, regulatory path and commercial value together.

A cardiologist says the ECG-AI result is useful but does not fit into their workflow. What do you do?

What they are checking: Whether they see clinical workflow integration as part of the product, not an afterthought.

You need alignment between the Technology and Science organizations, and they want different things. How do you handle it?

What they are checking: Ability to align groups with different goals around a shared roadmap.

How do you work with data scientists when the model's performance on a subgroup is weaker than expected?

What they are checking: Whether they take bias and generalizability seriously in a clinical AI product.

About the work

Walk me through the SaMD lifecycle as you have experienced it. Where do product managers most often get it wrong?

What they are checking: Real experience bringing software as a medical device to market, not just reading about it.

How do design controls and risk management change the way you write requirements?

What they are checking: Understanding that requirements in a regulated product must be traceable to risk and verification.

How would you integrate an AI result into an EHR so physicians actually see and act on it?

What they are checking: Familiarity with EHR integration and how point-of-care delivery shapes adoption.

What would you track in post-market surveillance for an AI cardiac device?

What they are checking: Awareness of performance drift, complaints and real-world monitoring after clearance.

How do you measure whether an ECG-AI product is succeeding after launch?

What they are checking: Whether they connect clinical impact, adoption and business results.

Practice this interview out loud.

Offer builds a real interview for this exact role at Tempus AI from your resume and this job description, asks the questions one at a time, and tells you what landed. The first one is free.

Practice this out loud

The full job description

As published by Tempus AI.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. As a Senior Product Manager for Order Processing at Tempus, you are critical to enabling assay productionalization initiatives and developing tools to improve operational efficiency. What You'll Do: • Develop and manage the product roadmap for the Order Processing team, ensuring alignment with Tempus' strategic goals. • Envision and articulate a clear, inspiring path forward, identifying key milestones and setting ambitious yet achievable targets. • Work closely with engineering, design, commercial, and operations teams to drive the planning, design, and development of solutions. • Partner with leadership and cross-functional product teams to develop project plans and set targets as part of quarterly planning; be accountable for achieving those targets. • Develop a deep understanding of the Order Processing domain as well as broader end-to-end order fulfillment. • Coordinate with various stakeholders to ensure the product meets the needs of all users, including clinicians, patients, and internal teams. • Oversee product releases, ensuring they are stable in production and meet scalability, reliability, and performance goals. • Cultivate and drive improvements to order management processes, ensuring efficiency and effectiveness. • Distill, refine, and document information and implementation requirements across Tempus' teams, utilizing AI-assisted workflows to ensure precision and speed. • Lead operational change management for production changes and any related workflow impacts. • Triage and act on product support requests. Qualifications: • 6+ years of experience in product management. • Outstanding cross-functional leadership skills, with proven experience managing complex projects through influence. • A proven track record of translating research into design and product decisions. • Demonstrated ability to manage several programs at once and work proactively to align multi-disciplinary stakeholders. • Exceptional storytelling and communication skills, capable of explaining complex concepts in simple terms. • An entrepreneurial spirit, with a proclivity to roll up your sleeves and work on everything from strategy to execution. • Experience building and developing high-performing teams. • AI-Fluency: Leverages Generative AI to accelerate individual productivity and applies a strategic vision for incorporating an agentic-first approach into product solutions • A growth mindset and a desire to continuously learn. • Highly organized with strong attention to detail and a pervasive bias toward clarity and scalability. • Ability to thrive in a fast-paced environment. • Knowledge of healthcare and experience in is ideal #LI-Hybrid #LI-HR1 CHI: $110,000-$160,000 The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Apply at Tempus AI

More senior product manager roles