Registered Nurse - RN - Oncology Chemotherapy/Infusion
Posted Sep 30, 2026 · We last checked this listing on Oct 6, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
Tell me about a time you kept an infusion schedule running when several patients came in late or needed extra time.
What they are checking: Whether they can manage a busy chair schedule without cutting safety corners.
Do you hold or plan to get your OCN or chemo-biotherapy certification? Tell me about your oncology training.
What they are checking: Whether they have the formal preparation infusion centers often expect for chemotherapy administration.
Tell me about a patient you built a long relationship with through treatment. What did you learn from it?
What they are checking: Whether they connect with patients over months while keeping professional boundaries.
What would you do
A patient arrives for treatment but their platelet count is lower than the parameters allow. What happens next?
What they are checking: Whether they hold treatment and contact the provider rather than proceeding on a busy chair schedule.
A patient on their eighth cycle tells you they want to stop treatment. How do you respond?
What they are checking: Whether they listen, explore the reason and bring in the provider, respecting autonomy without pushing either way.
About the work
Fifteen minutes into a first dose of a monoclonal antibody, your patient gets flushed, short of breath and has a tight chest. What do you do?
What they are checking: Whether they stop the infusion, follow the hypersensitivity protocol and stay with the patient while getting help.
Walk me through how you verify a chemotherapy order before you administer it.
What they are checking: Whether they check regimen, dose calculations, labs and patient identity with an independent second nurse.
How do you access a port and what would stop you from using it?
What they are checking: Whether they know sterile access, blood return checks and signs of malfunction or infection.
How do you protect yourself and coworkers when handling hazardous drugs?
What they are checking: Whether they consistently use proper PPE, closed systems and spill procedures.
What teaching do you give a patient leaving with a home infusion pump?
What they are checking: Whether they can teach pump alarms, spill handling and when to call so patients stay safe at home.
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Practice this out loudThe full job description
As published by Trinity Health.