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Project Manager, Diagnostic Operations

Tempus AI · Chicago, IL · Full time

Posted Sep 28, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a cross-functional project you managed in a clinical or operations setting. How did you keep it on track?

What they are checking: Whether they have real experience driving projects across teams with competing priorities.

Tell me about a process you improved with data. What changed?

What they are checking: Whether they connect operational excellence work to measurable outcomes.

Tell me about a project that failed or was canceled. What did you learn?

What they are checking: Whether they reflect honestly and apply lessons rather than hiding failures.

What would you do

You're handed three projects in different areas of the diagnostics business on the same week. How do you get up to speed?

What they are checking: Whether they can learn new areas fast in a broad role that changes often.

A project depends on a team that keeps missing deadlines. What do you do?

What they are checking: Whether they find the root cause and escalate thoughtfully instead of just reminding people.

How do you report project status to leaders so they know when to step in?

What they are checking: Whether they share risks early and clearly instead of saying green until it turns red.

How do you manage change when a new process affects lab staff who didn't ask for it?

What they are checking: Whether they involve frontline teams and plan for adoption, not just rollout.

About the work

How do you scope a project when the problem is vague, like turnaround times feel too slow?

What they are checking: Whether they turn a vague concern into a defined problem with measurable goals.

What tools do you use to plan and track projects, and how do you keep them from becoming busywork?

What they are checking: Whether they use project tools to drive decisions, not just to report status.

In a regulated clinical lab, what extra steps do you build into a project plan?

What they are checking: Whether they plan for validation, documentation and quality approvals in a CLIA environment.

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The full job description

As published by Tempus AI.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Project Manager, Diagnostic Operations Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus is a technology company at the forefront of precision medicine, advancing healthcare through AI-driven diagnostics and real-world evidence. Our diagnostics business sits at the intersection of clinical operations, commercial outcomes, and data, serving physicians and health systems across oncology and genomics. We are building the operational infrastructure that will define how Tempus scales its diagnostic operations. We're looking for a Project Manager to join our Operational Excellence team to support internal processes and initiatives that keep the diagnostics business unit running efficiently. This is a broad, cross-functional role: the Project Manager will take on projects across a range of teams and workflows, partnering closely with stakeholders throughout the diagnostics organization to improve how work gets done. They will serve as a subject matter expert for the operating systems that support diagnostics operations, lead process improvements, and own operational reporting that leadership can rely on as a source of truth. Additionally, the Project Manager will support operational communications and other projects as identified. Responsibilities: • Partner with cross-functional teams across the diagnostics business unit to execute operational initiatives and workflow improvements, spanning a range of teams, systems, and processes • Serve as a subject matter expert for the operating systems and tools that support diagnostics operations, helping to ensure data integrity, security, and efficient performance across workflows • Autonomously own ad hoc process improvements and new initiatives to ensure operational excellence is maintained as the business scales • Implement and maintain tracking systems for operational initiatives and project status • Build and maintain reports and dashboards that give leadership a clear, accurate view of workflow performance and key metrics; partner with Business Intelligence to identify KPIs, validate data accuracy, and iterate as business needs evolve • Perform hands-on data work as needed, including pulling and combining operational data across source systems to support reporting and process decisions • Support operational communications across the diagnostics network and stakeholder teams • Partner cross-functionally with Business Intelligence, Commercial Systems/SFDC, Product, and Internal Operations teams to identify gaps, align on decisions, and keep initiatives moving Qualifications : • Bachelor's degree, preferably in Life Sciences, Healthcare Administration, Business, or a related analytical field • 2-4 years of relevant experience in operations, project management, healthcare/diagnostics, or data and analytics • Must be a self-starter who can work independently with minimal supervision • Persistent and resilient person who thrives in a fast-paced, highly iterative environment • Is highly organized and systematic, with superb attention to detail and the ability to prioritize and complete tasks with a high degree of accuracy • Excellent written and verbal communication skills, including the ability to translate operational detail into a clear story for leadership • Comfort working with data: familiarity with SQL and data visualization tools (Looker preferred; Tableau acceptable), or a strong willingness to build these skills • Proficiency with CRM and operating systems (Salesforce/SFDC) and general database management • Proficiency with MS Office (Word, Excel, PowerPoint) and Google Suite (Sheets, Docs, Slides) Nice to Haves: • Experience in healthcare diagnostics, oncology, or life sciences • Familiarity with clinical and lab data systems (LIMS, EMR) • Experience building dashboards or operational reporting CHI: $65,000-$80,000 The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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