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Laboratory Safety Manager

Tempus AI · Chicago, IL · $85,000–$117,000 a year · Full time

Posted Oct 2, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a safety policy you wrote or rewrote. What prompted it, and how did you get people to actually follow it?

What they are checking: Whether they can turn a written policy into changed behavior on the bench, which is the hard part.

Tell me about a time you found a serious compliance gap during an audit. How did you report it and what changed?

What they are checking: Whether they surface bad news clearly to leadership and follow through until the fix is real.

Tell me about a time you had to shut down or pause work for a safety reason. How did you make that call?

What they are checking: Whether they have the judgment and backbone to stop work when it is warranted and explain why.

What would you do

You walk through a lab and find SDS binders that are incomplete and a few chemicals with no sheet at all. What do you do that day and that month?

What they are checking: Whether they separate the immediate fix from the system change that keeps the gap from coming back.

A busy lab supervisor tells you the new safety step will slow turnaround times and they won't enforce it. How do you handle that?

What they are checking: Whether they can hold a safety line while still respecting the pressure the lab is under.

How do you design safety training that lab staff remember, instead of a slide deck they click through once a year?

What they are checking: Whether they understand that a culture of safety comes from practical, repeated training rather than annual sign-offs.

About the work

You're responsible for safety across labs that answer to CAP/CLIA, New York State, OSHA, FDA and DOT. How do you keep track of where those rules overlap and where they differ?

What they are checking: Whether they have a working system for layered regulations rather than reacting to whichever inspector shows up next.

How would you set up hazardous chemical and biohazard waste handling across several lab areas, including working with outside disposal vendors?

What they are checking: Whether they know the full chain from generation to manifest to vendor pickup and where it usually breaks.

Walk me through how you would investigate a needlestick or chemical splash incident from report to closeout.

What they are checking: Whether they look for root cause and corrective action instead of stopping at filling out the incident form.

How do you build an emergency management plan for a lab, and how do you know it would actually work?

What they are checking: Whether they test plans with drills and exercises rather than trusting a document no one has rehearsed.

What safety metrics would you track for a set of clinical labs, and which ones would you worry are misleading?

What they are checking: Whether they know low incident counts can mean underreporting and look for leading indicators too.

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The full job description

As published by Tempus AI.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. The Laboratory Safety Manager oversees enterprise safety and emergency management policies, ensures regulatory compliance across all laboratory operations, and champions a culture of safety among lab staff. This role combines hands-on safety program management with training, auditing, and continuous process improvement responsibilities. What You’ll Do • Oversee enterprise safety and emergency management policies. • Develop, review, revise, and maintain laboratory safety policies. • Understand, advise staff, and ensure compliance with CAP/CLIA, NYS, OSHA, FDA, and DOT regulations with regard to safety. • Monitor the use and disposal of chemicals and biohazardous materials from all lab areas per state and federal guidelines and coordinate with external vendors for hazardous waste disposal. • Manage and update Safety Data Sheets (SDS) for all labs and ensure all SDS binders are complete and up to date. • Manage incident and event reporting for any safety incidents or events. • Establish and enforce appropriate PPE protocols for laboratory staff. • Provide training and ensure all lab staff have completed safety training and are current on their annual quizzes and/or updates to safety protocols. • Ensure personnel have knowledge and training for how to respond to emergencies including but not limited fires, spills, exposures, and forces of nature. • Ensure safety equipment is maintained according to requirements (eye wash, fire extinguishers, showers, first aid kits, etc.). • Complete and document monthly safety audits to address issues within the laboratory. • Conduct and oversee new-hire laboratory safety training and annual fire safety training for content and completeness. • Prepare for and participate in laboratory audits and meet with Quality and Management teams as needed. • Write policies and procedures to meet safety code compliance for the lab. • Assess ergonomic risk and provide solutions to lab and workstation ergonomics. • Oversee accident investigation process and work with laboratory management to determine corrective/preventative actions in response to workplace injuries. • Serve as chair of the safety committee. Facilitates safety discussions, contributing observations and listening to feedback. • Prepare safety training material. Delivers safety training to team members. • Lead and manage assigned staff. • Additional job duties as assigned. Qualifications • Bachelor’s degree in industrial hygiene, environmental health, chemistry, biology, or a closely related scientific field. • At least 5 years of experience in an EHS-related role is desired. • Experience working in CLIA/CAP laboratory is desired. • Knowledge of state and federal safety regulations for work environment and personnel. • Prior supervisory experience is preferred. • Excellent communication skills. • Thrives in a fast-paced environment. • Ability to work independently as well as with others to plan and carry out projects. • Self-driven and works well in an interdisciplinary team with minimal direction. • Ability to multi-task and remain flexible to the changing needs of the business • Experience using hand tools and basic understanding of electrical systems • Ability to work with cleaning supplies and chemicals with appropriate personal • protective equipment (PPE) • Ability to lift 50 lbs • Ability to stand, bend, reach, and lift repeatedly for extended periods of time • Remain in standing, walking, and bending position for extended periods of time Chicago Pay Range: $85,000-$117,000 The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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