Jobs › Tempus AI

Senior Vice President, Medical Affairs

Tempus AI · NY · Remote available · $365,000–$475,000 a year · Full time

Posted Jul 14, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about leading Medical Affairs at a cancer-focused company. What did you build and what would you change?

What they are checking: Whether they have truly led the function and can reflect honestly on what worked and what did not.

You lead multidisciplinary teams of data scientists and PhDs. How do you get them to communicate clearly with physicians?

What they are checking: Whether they can turn deep technical work into messages clinicians understand and trust.

How does your clinical practice experience shape the way you lead a medical affairs team?

What they are checking: Whether they bring real bedside perspective and use it to keep the team grounded in patient care.

Tell me about a time you had to disagree with a CEO or commercial leader on a medical matter.

What they are checking: Whether they have the judgment and nerve to hold a medical position at the executive table.

What would you do

How would you build partnerships with large health systems around molecular diagnostics and real-world data?

What they are checking: Whether they can see what health systems want, such as research, care quality or trials, and offer real value.

A marketing piece overstates what a test can do. Sales wants it out this week. What do you do?

What they are checking: Whether they protect accuracy under pressure and can resolve it without starting a war with commercial.

How would you hire and develop a medical affairs team that keeps pace with a fast-growing company?

What they are checking: Whether they can scale a team thoughtfully, balancing speed with quality and culture.

About the work

How would you structure speaker programs so they are educational and compliant, not promotional?

What they are checking: Whether they understand the compliance rules for speaker programs and how to keep scientific credibility.

How should medical input shape commercial strategy and marketing materials in a diagnostics company?

What they are checking: Whether they can guide commercial teams with evidence while holding a firm line on accurate claims.

What role should large real-world data sets play in medical communications?

What they are checking: Whether they can use real-world evidence responsibly and explain its limits to external audiences.

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The full job description

As published by Tempus AI.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. We are looking for a Senior Vice President of Medical Affairs to join the Medical Science Department at Tempus. The candidate will have experience leading Medical Affairs for a cancer focused company. At least 10 years of clinical practice and experience is required. A knowledge base in molecular diagnostics, precision oncology, health systems, clinical research, and use of large data sets/real world data and medical communications is required. Responsibilities Include: • Serve as a physician leader and speaker for Tempus’ Medical Affairs department • Help establish and build clinical relationships and health system partnerships. • Help oversee Tempus speaker programs. • Lead multidisciplinary teams of data scientists and PhDs to provide external facing communications and customer interactions for the company • Provide medical input into commercial strategies, disease-state speaker programs, and marketing materials to ensure scientific integrity. • Provide medical oversight to elevate corporate documentation and marketing materials through the medical legal review process • Translate voice of customer and market insights to Tempus leadership Required Qualifications: • MD degree with oncology clinical training (breast or GI oncology preferred) • 10 years of clinical practice and experience required • Previous experience leading teams of medical professionals, physicians, communication specialists and commercial experts • Clinical research and study design experience • Experience defining a medical affairs strategy in a corporate setting preferred • Strong communication skills regarding the Tempus mission and strengths • Innovative thinking regarding building external partnerships with individual investigators, academic institutions, cooperative groups and non-profit organizations • A mindset for execution US Salary Range: $365,000- $475,000 The expected salary range above is applicable if the role is performed from New York and may vary for other locations (California, Colorado, Illinois). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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