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(Senior) Medical Director, Oncology Life Sciences Research

Tempus AI · IL · Remote available · Full time

Posted Sep 14, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about your clinical experience in GI or breast cancers and how it shapes the way you think about drug development.

What they are checking: Whether their bedside experience translates into credible judgment about trial design and unmet need.

Tell me about a time you translated a messy clinical problem into a clear data question someone could actually answer.

What they are checking: Whether they can bridge physicians and data scientists, which is the core of a role between clinic and data.

Describe a time you had to influence senior people at a client who outranked you in their own organization.

What they are checking: Whether they can lead through expertise and preparation when they have no formal authority.

What would you do

A biopharma partner is struggling to enroll a GI cancer trial. How would you use real-world data to help them?

What they are checking: Whether they can turn feasibility, site selection and patient-finding into concrete actions using multimodal real-world data.

What would a long-term clinical strategy for a key pharma account look like, and how would you build it?

What they are checking: Whether they think past one project to how the partnership grows over years across data, AI tools and trials.

An account team wants you to back a claim to a client that you think the data does not quite support. What do you do?

What they are checking: Whether they protect scientific integrity under commercial pressure, since their credibility is the asset they bring.

How do you prioritize when several account teams all want your time on the same week?

What they are checking: Whether they can triage requests by impact and say no clearly without damaging internal relationships.

About the work

How would you explain the strengths and limits of real-world evidence to a pharma team used to randomized trial data?

What they are checking: Whether they can speak honestly about bias, missingness and confounding while still showing where the data adds value.

How do you see agentic AI tools changing the way biopharma teams run oncology research?

What they are checking: Whether they have a grounded view of AI that neither dismisses it nor oversells what it can do today.

How would you stay current on breast and GI oncology while working outside daily clinical practice?

What they are checking: Whether they have a real plan to keep their clinical knowledge sharp, since stale expertise loses clients' trust.

Practice this interview out loud.

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The full job description

As published by Tempus AI.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Tempus is seeking a (Senior) Medical Director in Oncology to serve as the primary clinical partner for our Life Sciences account teams. This role bridges the gap between clinical oncology practice, real-world data, and biopharma drug development. You will partner with key accounts to provide strategic, proactive clinical guidance. You will translate complex oncologic concepts, patient care realities, and clinical trial challenges into actionable data and AI-driven solutions. The ideal candidate brings dedicated clinical experience in Gastrointestinal (GI) or Breast malignancies, combined with a strong understanding of how real-world evidence accelerates oncology pipelines. Responsibilities • Build and execute holistic, long-term clinical strategies for assigned accounts, leveraging Tempus capabilities including multimodal real-world data (RWD) datasets, agentic AI tools, and clinical trial acceleration solutions. • Serve as the primary clinical peer to biopharma Clinical Directors, Medical Affairs leaders, and Translational Medicine executives, maintaining a proactive, structured cadence of engagement. • Develop indication-specific "battle decks" that map real-world standards of care, biomarker testing patterns, and unmet clinical needs directly against client pipeline assets. • Analyze client pipelines, clinical trial readouts, and investor relations materials to proactively anticipate client needs and formulate strategic account growth plans. • Synthesize medical conference updates (e.g., ASCO, ESMO, SABCS) into actionable client insights, advising biopharma partners on trial protocol design, cohort selection, and synthetic control arms. • Partner with internal teams on high-value client calls to communicate complex scientific and clinical solutions with authoritative credibility. • Act as an internal subject matter expert across Tempus products and services to ensure scientific accuracy, enhance product usability, and align service capabilities with evolving market needs. Qualifications • Education & Clinical Practice: MD or DO required, with board certification/eligibility in Medical Oncology • Subspecialty Expertise: Strong clinical focus in Gastrointestinal (GI) or Breast cancers is highly preferred. • Biopharma & RWD Fluency: Proven ability to analyze biopharma drug pipelines, understand clinical trial design/regulatory pathways, and apply complex real-world datasets (NGS, clinical data) • Executive Presence: Track record of building trusted relationships with biopharma leadership, leading complex enterprise initiatives, and presenting to executive client teams. #LI-NK1 #LI-REMOTE $270,000-$350,000 The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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