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Senior Enterprise Architect

PCI Pharma Services · Rockford, IL · Full time

Posted Jun 5, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about an architecture review board you've led. How did you keep it from becoming a bottleneck?

What they are checking: Whether they can govern decisions while still letting teams move fast.

Tell me about technology due diligence you've done for an acquisition.

What they are checking: Whether they know what to look for in an M&A target's systems and integration risks.

How do you mentor engineers on architecture principles without micromanaging their designs?

What they are checking: Whether they can raise the skill of the team through coaching.

What would you do

An MSP submits a design that doesn't meet our standards, but the project is under deadline. What do you do?

What they are checking: Whether they can hold standards while helping find an acceptable path forward.

How do you align technology architecture with business goals when leaders disagree on priorities?

What they are checking: Whether they can facilitate trade-off discussions and connect tech choices to business outcomes.

About the work

How would you design a reference architecture that spans Azure, AWS and on-premises for a global pharma services company?

What they are checking: Whether they can make clear choices about workload placement, identity and network across environments.

Walk me through how you would design IT/OT architecture for a manufacturing plant with validated systems.

What they are checking: Whether they understand network segmentation, OT security and the constraints of GxP systems.

How do you run a build versus buy analysis for a major platform decision?

What they are checking: Whether they weigh cost, risk, skills and long-term ownership instead of personal preference.

How would you define a strategy to manage technical debt across many acquired sites?

What they are checking: Whether they can prioritize modernization by risk and business value.

How do you approach cloud cost optimization without hurting performance or compliance?

What they are checking: Whether they understand FinOps practices and the trade-offs involved.

How do you document architecture decisions so they still make sense to someone two years from now?

What they are checking: Whether they use decision records and diagrams that capture why, not just what.

Practice this interview out loud.

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The full job description

As published by PCI Pharma Services.

Life changing therapies. Global impact. Bridge to thousands of biopharma companies and their patients. We are PCI. Our investment is in People who make an impact, drive progress and create a better tomorrow. Our strategy includes building teams across our global network to pioneer and shape the future of PCI. Key Responsibilities • Develop enterprise architecture frameworks and technology standards for infrastructure and security domains • Create reference architectures for cloud (Azure, AWS), hybrid, and on- premises environments • Lead architecture review board and provide governance for significant technology decisions • Evaluate emerging technologies and provide strategic recommendations (build vs. buy analysis) • Design IT/OT architecture patterns for manufacturing and industrial environments • Establish cloud strategy including multi-cloud governance, workload placement, and cost optimization • Review and approve MSP solution designs ensuring alignment with enterprise standards • Define technical debt management strategy and modernization roadmap • Create architecture documentation including diagrams, decision records, and standards catalogs • Mentor technical staff on architecture principles and best practices • Support M&A activities with technology due diligence and integration architecture • Align technology architecture with business capabilities and strategic objectives Required Qualifications • Bachelor’s degree in computer science, Engineering, or related field • 10+ years of progressive IT experience with 5+ years in enterprise architecture roles • Demonstrated experience developing enterprise architecture for organizations of 5,000+ users • Deep expertise in cloud architecture (Azure and/or AWS) with hands-on design experience • Strong infrastructure architecture knowledge (compute, storage, network, virtualization) • Experience with architecture frameworks (TOGAF, Zachman, or similar) • Excellent communication skills for presenting to executive and board audiences • Strong vendor management and technology evaluation capabilities • Experience in regulated industries with compliance architecture requirements Preferred Qualifications Master’s degree in technology or business administration • TOGAF 9.x certification • Azure Solutions Architect Expert or AWS Solutions Architect Professional • Pharmaceutical or manufacturing industry experience • Experience with IT/OT convergence and industrial architecture • Knowledge of Zero Trust architecture implementation Technical Skills & Tools Azure architecture (landing zones, hub-spoke, governance) • AWS architecture (Well-Architected Framework) • VMware vSphere / Cloud Foundation • Cisco enterprise networking • Storage architecture (SAN, NAS, object storage) • Identity architecture (Entra ID, AD) • Security architecture patterns • Veeam / enterprise backup architecture • Architecture modeling tools (Visio, LucidChart, ArchiMate) Key Performance Indicators • Architecture standards documentation (target: complete framework in 6 months) • Architecture review board effectiveness (target: 100% major projects reviewed) • Technical debt reduction (target: 20% reduction in legacy systems YoY) • Cloud cost optimization (target: 15% efficiency improvement) • Stakeholder satisfaction (target: >4.0/5.0) Join us and be part of building the bridge between life changing therapies and patients. Let’s talk future Equal Employment Opportunity (EEO) Statement: PCI Pharma Services is an Equal Opportunity/Affirmative Action Employer. We do not unlawfully discriminate on the basis of race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status, or any other protected status. At PCI, Equity and Inclusion are at the core of our company’s purpose: Together, delivering life-changing therapies. We are committed to cultivating an inclusive workplace by holding ourselves accountable to the highest standards of understanding, fairness, respect, and equal opportunity – at every level. We envision a PCI community where everyone can belong and grow, and we strive to bring this vision to reality by continuously and intentionally assessing our people practices, policies and programs, marketing approach, and workplace culture.

Apply at PCI Pharma Services