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Respiratory Therapist, PRN Nights

City of Hope Chicago · Zion, IL · Part time

Posted Aug 25, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time you disagreed with a physician's order for respiratory treatment. How did you handle it?

What they are checking: Professional confidence to raise concerns and use protocols to support patient safety.

How do you prepare a patient and family for extubation or a change to comfort care?

What they are checking: Compassion and communication during end-of-life respiratory care, common in oncology.

Which credentials do you hold, such as RRT and ACLS, and what ventilators have you used most?

What they are checking: Readiness to work independently at night with minimal orientation.

What would you do

As PRN nights, you need to work at least three shifts every six weeks. How would you keep your skills and knowledge of our protocols current?

What they are checking: Commitment to staying sharp and familiar with the unit despite a limited schedule.

How do you prioritize when you are the only therapist in the hospital at night and two calls come at once?

What they are checking: Triage judgment when coverage is thin and both calls might be urgent.

About the work

You are called to a rapid response for a patient with sudden shortness of breath and low oxygen. Walk me through what you do.

What they are checking: Fast airway and breathing assessment and choosing the right oxygen or support device.

How do you manage a patient on BiPAP who is getting more agitated and less able to tolerate the mask?

What they are checking: Knowing when noninvasive support is failing and when to escalate to intubation.

Your ventilated patient's peak pressures suddenly rise. What do you check?

What they are checking: A methodical approach to ventilator troubleshooting that separates patient causes from circuit causes.

Cancer patients often have fragile lungs from treatment. How does that change your approach?

What they are checking: Awareness of lung toxicity from chemo and radiation and immunosuppressed patients' infection risks.

What is your role in a code, and what do you focus on from the moment you arrive?

What they are checking: Clear understanding of airway management and teamwork during a cardiac arrest.

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The full job description

As published by City of Hope Chicago.

Respiratory Therapist, PRN Nights About City of Hope , City of Hope's mission is to make hope a reality for all touched by cancer and diabetes. Founded in 1913, City of Hope has grown into one of the largest and most advanced cancer research and treatment organizations in the U.S., and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center that is ranked top 5 in the nation for cancer care by U.S. News & World Report at its core, City of Hope’s uniquely integrated model spans cancer care, research and development, academics and training, and a broad philanthropy program that powers its work. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and cancer treatment centers and outpatient facilities in the Atlanta, Chicago and Phoenix areas. The successful candidate: Schedule • Status: PRN (As Needed) • Shift: 12‑hour shifts, Nights • Hours: 7:00 PM – 7:00 AM • Minimum Requirement: Must be available to work at least three (3) shifts per schedule period (every 6 weeks) . Additional shifts may be available based on department needs. Job Responsibilities Performs all offered respiratory therapies, ventilator management, EKG’s, Pulse oximetry, pulmonary function tests and special procedures via Pulmonologist and Nursing Manager. Operates and manages respiratory equipment and supplies to ensure safe and accurate patient care. Performs and assists in training of new/temporary Respiratory Therapists within scope of practice and experience. Performs clerical duties such as chart data entry, input of department charges, document filing, and other tasks as assigned Position Qualifications Minimum Education • Graduate of an accredited respiratory therapy program Required Certification/Licensure • Current Illinois Respiratory Therapist license • CPR certification Preferred Certification/Licensure • ACLS • National Certification (RRT) Preferred Experience • Minimum of three (3) years of critical care/ICU experience preferred Skills & Abilities • Strong background in bedside patient care • Self‑motivated and able to work independently • Strong organizational and attention‑to‑detail skills Software • Basic computer skills, including Microsoft Word and Excel City of Hope is an equal opportunity employer. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. Please note : City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews. • Apply only through our official website or trusted partner platforms. • City of Hope will never request payment or fees at any stage of the hiring process. • We will not request sensitive personal or financial information prior to the acceptance of a formal offer. • All communications will come from official @coh.org email addresses. • Interviews are conducted only through approved, professional channels. • Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices. • If you receive any suspicious communication, please report it to careers@coh.org .

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