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Research Technologist III - Physiology

Medical College of Wisconsin · Milwaukee, WI · Full time

Posted Sep 28, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time you supported biosafety compliance or prepared for an inspection.

What they are checking: Whether they take biosafety rules seriously and keep the lab ready for review.

What would you do

This role is part lab manager. How would you set up systems for ordering, inventory and equipment maintenance in a busy lab?

What they are checking: Whether they can run lab operations smoothly so researchers can focus on science.

How do you train a new lab member in safety and basic techniques?

What they are checking: Whether they can teach clearly and check that safety habits really stick.

Two lab members want the same piece of equipment at the same time for urgent work. How do you handle it?

What they are checking: Whether they can manage shared resources fairly and calmly.

How do you balance lab management tasks with your own experiments and analysis?

What they are checking: Whether they can plan their time so neither side of the job falls behind.

About the work

Walk me through a bioinformatics analysis you've done in R or Python, start to finish.

What they are checking: Whether they have real working skill in the dry-lab tools the posting requires.

How comfortable are you working on a Linux command line or a computing cluster?

What they are checking: Whether they can run analyses on the systems this lab actually uses.

Tell me about your mammalian cell culture experience, including any hard-to-grow cell types.

What they are checking: Whether they have the strong wet-lab skills the posting asks for.

How do you keep protocols, notebooks and data files organized so anyone in the lab can find them?

What they are checking: Whether they build shared documentation that outlasts any single person.

What do you know about epigenetics, such as histone modifications or DNA methylation?

What they are checking: Whether they understand the basics of the lab's research focus on epigenetic regulation.

How do you make your analysis code reproducible for other lab members?

What they are checking: Whether they write documented, versioned code instead of one-off scripts.

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The full job description

As published by Medical College of Wisconsin.

Summary We seek a responsible, experienced, and highly organized Research Technologist III to manage laboratory operations and support ongoing research projects in the laboratory of Dr. Yang Xiao in the Department of Physiology at the Medical College of Wisconsin. Our research focuses on the epigenetic regulation of hepatic and cardiac physiology. This position combines laboratory management with wet-lab experimentation and dry-lab data analysis. The Research Technologist III will help ensure efficient daily laboratory operations and supporting research personnel. For the wet-lab component, the ideal candidate will have strong experience with mammalian cell culture. For the dry-lab component, basic bioinformatics skills and working knowledge of Linux, R, and Python are required. Primary Responsibilities • Assist with daily laboratory operations, including ordering supplies, maintaining inventory, coordinating equipment maintenance, organizing shared laboratory resources and supporting laboratory biosafety compliance. • Maintain laboratory documentation, including experimental protocols, laboratory notebooks, data files, training records, equipment logs, and reagent inventories. • Train and provide technical guidance to new laboratory members in laboratory safety and basic experimental techniques. • Perform mammalian cell culture work • Perform bioinformatics analysis • Participate in regular laboratory meetings with the Principal Investigator and research staff to discuss experimental progress, interpret results, and troubleshoot technical challenges. • Other duties as assigned Knowledge – Skills – Abilities • Knowledge of laboratory management, protocol administration, and research record management. • Strong resource, inventory, and vendor-management skills. • Experience with mammalian cell culture and aseptic techniques. • Experience with relevant molecular and biochemical techniques is preferred. • Ability to perform quantitative, statistical, bioinformatics, or other dry-lab data analysis. • Ability to train and provide technical guidance to students, trainees, and new laboratory personnel. • Strong organizational, communication, problem-solving, and time-management skills. • Ability to manage multiple responsibilities and work independently with limited supervision. Qualifications Appropriate experience may be substituted for education an on equivalent basis. Minimum Required Education: Bachelor’s degree Minimum Required Experience: Three years of relevant research or laboratory experience Preferred Education: Master’s degree in a relevant scientific discipline Preferred Experience: Laboratory management, mammalian cell culture, molecular or biochemical techniques, and dry-lab data analysis Field: Biology, biomedical sciences, biochemistry, molecular biology, or a related scientific field Physical Requirements Work requires occasionally lifting moderate weight materials, standing, or walking continuously. Risk Potential Little or no exposure to hazards such as dust, fumes, or extreme temperatures, airborne or blood borne pathogens, extreme temperatures, or allergens. Sensory Acuity Ability to detect and translate speech or other communication required. May occasionally require the ability to distinguish colors and perceive relative distances between objects. Work Environment Occasional exposure to dust, noise, temperature changes, or contact with water or other liquids. Work is performed in an environmentally controlled environment. Why MCW? • Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options • 403B Retirement Package • Competitive Vacation and Paid Holidays offered • Tuition Reimbursement • Paid Parental Leave • Employee & Family Assistance Program (EFAP) • Pet Insurance • On campus Fitness Facility, offering onsite classes • Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc. For a brief overview of our benefits see: Benefits Overview For a full list of positions see: MCW Careers At MCW all of our endeavors, from our internal operations to our interactions with our partners, are driven by our shared organizational values: Caring – Collaborative – Curiosity – Inclusive – Integrity – Respect. We are committed to fostering an inclusive environment that values diversity in backgrounds, experiences, and perspectives through merit-based processes and in alignment with all applicable laws. We believe that embracing human differences is critical to realize our vision of a healthier world, and we recognize that a healthy and thriving community starts from within. Our values define who we are, what we stand for and how we conduct ourselves at MCW. If you believe in embracing individuality and working together according to these principles to improve health for all, then MCW is the place for you. For more information, please visit our institutional website . MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination: The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

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