Registered Nurse (RN) - Oncology Infusion
Posted Sep 8, 2026 · We last checked this listing on Oct 6, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
Tell me about a time a patient had a reaction during infusion. What did you notice first and what did you do in the next few minutes?
What they are checking: ability to recognize and respond to acute reactions like anaphylaxis or extravasation under pressure
Tell me about a time you had to give a patient or family member bad news or manage their fear about a treatment. How did you approach that conversation?
What they are checking: compassionate communication skills specific to oncology patients under stress
Describe a situation where you disagreed with a physician or another team member about a patient's care plan. How did you handle it?
What they are checking: comfort with interdisciplinary collaboration and patient advocacy without creating conflict
Tell me about a time you caught an error, either your own or someone else's, before it reached the patient.
What they are checking: honesty and commitment to safety culture rather than covering mistakes
Tell me about a time the emotional weight of oncology nursing got to you. How did you take care of yourself and still show up for your next patient?
What they are checking: self-awareness and sustainability in a role with high emotional demands and no built-in downtime
What would you do
A patient shows up for their scheduled infusion but their labs from that morning haven't come back yet and it's getting close to closing time. What do you do?
What they are checking: judgment about patient safety versus clinic flow pressure, and willingness to hold treatment when needed
How do you manage your patient assignments when you have several people infusing at different rates and one of them suddenly needs more attention?
What they are checking: prioritization and multitasking in a busy ambulatory infusion setting
If a patient's condition changes quickly, say they become hypotensive or short of breath mid-infusion, walk me through exactly what you'd do first, second, and third.
What they are checking: clarity and speed of clinical decision-making in an emergency without immediate physician presence
How do you keep yourself and your patients on schedule in a clinic that closes at 5, when infusions can run long or patients arrive late?
What they are checking: time management and realistic expectations about the pace of an outpatient infusion clinic
About the work
Walk me through how you verify chemotherapy orders before you spike the bag. What do you check and who else has to sign off?
What they are checking: knowledge of chemo verification protocols and double-check safety standards
How do you handle vesicant administration and what would you do if you suspected an extravasation was happening?
What they are checking: specific clinical knowledge of high-risk drug handling and complication management
What's your process for handling chemotherapy spills or exposure to hazardous drugs, and what protective steps do you take day to day?
What they are checking: familiarity with hazardous drug handling standards and personal safety practices
How do you start and maintain IV access in patients who've had many rounds of treatment and have difficult veins?
What they are checking: hands-on IV insertion skill and patience with a challenging patient population
What does patient education look like for someone starting a new chemo regimen, and how do you make sure they actually understand what to watch for at home?
What they are checking: teaching ability and thoroughness in discharge and self-care instructions
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As published by Advocate Health.