Principal Research Scientist II Central Core Function Operations Leader
Posted Aug 11, 2026 · We last checked this listing on Sep 22, 2026
Likely interview questions for this role
Written from this job description, not a generic list. Each one notes what the interviewer is really checking.
About your past
You would oversee vendor relationships and outsourcing. Tell me about holding an outsourced partner to a service expectation.
What they are checking: External partner oversight, named in both duties and qualifications.
You would lead a team across multiple functional areas. How do you manage people whose technical work you do not do yourself?
What they are checking: Leading specialists at arm's length from their bench work.
This asks for a doctorate with eight or more years, a master's with fourteen, or a bachelor's with sixteen, and is an operations leadership role rather than a bench science one. Why move to operations at this stage?
What they are checking: That they have chosen the operational track deliberately, not drifted into it.
What would you do
This role leads centralized operations supporting absorption, distribution, metabolism and excretion science, bioanalysis and translational sciences. How do you balance standardization against the flexibility scientists need?
What they are checking: The defining tension of a core operations role, stated in the leadership expectations.
A scientific team says a standardized process is slowing their science down. How do you respond?
What they are checking: Defending standardization without steamrolling the customers of the core.
You partner with scientific, technical, quality, automation, information technology and business stakeholders. How do you get clarity on who owns what when nobody has written it down?
What they are checking: Establishing roles across functions, named in the leadership expectations.
About the work
You would monitor operational performance through dashboards, metrics and business reviews. What metric actually tells you a laboratory core is healthy?
What they are checking: Whether they can pick a meaningful measure rather than list several.
You would strengthen laboratory support capabilities including automation and robotics. How do you decide what is worth automating in a scientific laboratory?
What they are checking: Automation judgment — payback, variability, scientist time.
The role asks you to anticipate operational risks and implement mitigation before they land. What operational risk in a laboratory core is most often missed?
What they are checking: Foresight grounded in real experience — sample integrity, instrument downtime, key person dependency.
How do you keep compliance expectations — quality systems, environment health and safety, instrument calibration — actually met day to day rather than at audit time?
What they are checking: Continuous compliance rather than periodic scramble.
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As published by AbbVie.