Jobs › Abbott

Principal Clinical Molecular Geneticist

Abbott · Abbott Park, IL · Remote available · $113,300–$226,700 a year · Full time

Posted Sep 30, 2026 · We last checked this listing on Oct 6, 2026

Apply at Abbott

Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time new evidence changed a variant classification you had already reported. What did you do?

What they are checking: Whether they own reclassification and make sure patients and clinicians are informed.

How do you mentor junior geneticists or variant scientists who are still learning to classify variants?

What they are checking: Leadership in building a consistent, high-quality team, which this senior role requires.

What would you do

A referring physician calls upset that your report doesn't give a clear answer. How do you handle it?

What they are checking: Whether they can explain uncertainty clearly and kindly without overstating the result.

How do you balance turnaround time pressure with the need to review each case carefully?

What they are checking: Whether they protect accuracy while still meeting the lab's service commitments.

PreventionGenetics is now part of Abbott's cancer diagnostics organization. How would you work with teams who come from a different testing background?

What they are checking: Ability to collaborate across a merged organization with different practices.

About the work

Walk me through how you review a germline NGS case, from data quality to signing the report.

What they are checking: Whether their sign-out process is thorough enough to protect patients from a wrong result.

How do you apply ACMG/AMP criteria to a variant when the evidence is borderline between likely pathogenic and VUS?

What they are checking: Judgment in variant classification, where small calls change patient care.

How do you handle copy number variants or structural variants that the pipeline may miss or misreport?

What they are checking: Awareness of NGS blind spots and when to confirm with another method.

This role maintains a portfolio of clinical tests. How do you decide when a test needs updating?

What they are checking: Whether they think about test content and performance as a product they are accountable for.

What CLIA and CAP requirements shape how you validate and report a clinical genetic test?

What they are checking: Regulatory knowledge that keeps the lab accredited and results defensible.

Practice this interview out loud.

Offer builds a real interview for this exact role at Abbott from your resume and this job description, asks the questions one at a time, and tells you what landed. The first one is free.

Practice this out loud

The full job description

As published by Abbott.

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: • Career development with an international company where you can grow the career you dream of. • An excellent retirement savings plan with a high employer contribution. • A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. • A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. Position Overview As a member of the PreventionGenetics team, you will help lead and advance our clinical molecular genetics services while working within Abbott’s broader cancer diagnostics organization. The Principal Clinical Molecular Geneticist reviews clinical DNA test data and test reports. This position maintains a Portfolio of clinical DNA sequencing tests and cultivates expertise in a subspecialty of genetic disease. The Principal Clinical Molecular Geneticist serves as a thought leader among the geneticist team, guiding process improvements and consulting on challenging cases. Essential Duties Include, but are not limited to, the following: • Review genetic testing data, conduct troubleshooting when necessary, review the scientific literature, interpret genetic variants, write/edit genetic test reports, and sign out laboratory test results for tests performed. • Curate gene panels to include comprehensive gene lists supported by scientific literature. • Coordinate and lead process improvement projects to drive cost savings, efficiencies, and productivity. • Troubleshoot technical problems, with the aid of technical staff, and ensure remedial action is taken whenever test systems deviate from the laboratory’s performance standards. • Serve as an exception handler and expert resource for colleagues regarding complex cases. • Participate in the selection of test methodology and take initiative to improve systems, processes, and procedures to drive quality in daily production. • Demonstrate the ability to develop and coach others. • Provide leadership by promoting communication and collaboration, proactively supporting employee development initiatives, promoting cross-functional collaboration and teamwork, and aiding in conflict resolution. • Ability to manage confidential information. • Effectively communicate cross-functionally to all levels within the company. Ability to establish and maintain effective working relationships by using appropriate interpersonal skills. • Ability to frequently and accurately communicate with employees, customers, health care providers, and vendors, including representing the company at conferences. • Thrive in a fast-paced, ever-changing environment and in project team situations. • Comply with company Standard Operating Procedures (SOPs), practices, and applicable professional, Federal, State, and local regulations and assure that the laboratory is in compliance. • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork. • Support and comply with the company’s Quality Management System policies and procedures. • Maintain regular and reliable attendance. • Ability to act with an inclusion mindset and model these behaviors for the organization. • Ability to work designated schedule. • Ability to work nights and/or weekends, as needed. • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day. • Ability to travel up to 10% of working time, which may include overnight/weekend travel. Minimum Qualifications • Must meet one of the following groups of criteria: • Doctoral Degree in a Chemical, Biological, or Clinical Laboratory science from an accredited institution; and • Certification by one of the following entities at the time of hire and maintained throughout employment; and: • American Board of Bioanalytics (ABB) as a High-Complexity Clinical Laboratory Director (HCLD); or • American Board of Medical Genetics and Genomics (ABMGG) in Laboratory Genetics and Genomics (LGG), Molecular Genetics, or Cytogenetics; or • Canadian College of Medical Geneticists (CCMG). • Medical Doctor or Doctor of Osteopathic Medicine Degree with 3+ years in a clinical lab with director oversight, certified in anatomical or clinical pathology, or both, by the American Board of Pathology or the American Osteopathic Board of Pathology at time of hire and maintained throughout employment in position. • Years of experience performing high complexity genetic testing. • 4+ years of post-certification experience reviewing and signing out clinical test reports; or • 7+ years of total experience reviewing and signing out clinical test reports or equivalent. • Current New York state Certificate of Qualification in appropriate areas of oversight as necessary or ability to obtain within 6 months. • Demonstrated ability to perform the Essential Duties of the position with or without accommodation. • Authorization to work in the United States without sponsorship. The base pay for this position is $113,300.00 – $226,700.00 In specific locations, the pay range may vary from the range posted. JOB FAMILY: Research and Discovery DIVISION: ONCO Cancer Diagnostics LOCATION: United States of America : Remote ADDITIONAL LOCATIONS: WORK SHIFT: Standard TRAVEL: No MEDICAL SURVEILLANCE: No SIGNIFICANT WORK ACTIVITIES: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Keyboard use (greater or equal to 50% of the workday) Abbott is an Equal Opportunity Employer of Minorities/Women/Individuals with Disabilities/Protected Veterans. EEO is the Law link - English: http://webstorage.abbott.com/common/External/EEO_English.pdf EEO is the Law link - Espanol: http://webstorage.abbott.com/common/External/EEO_Spanish.pdf

Apply at Abbott