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Pathologist Assistant II, Surgical Pathology - PNE

Northwestern Medicine · Chicago, IL · Part time · Health Care Provider

Posted Oct 5, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time you found a better or faster way to do something in the gross room.

What they are checking: Whether they improve processes, which the posting explicitly asks for.

How do you teach a resident to gross a specimen they have never seen before?

What they are checking: Teaching skill, since the role supports resident training.

What would you do

You open a container and the label doesn't match the requisition. What do you do?

What they are checking: Stopping the process and resolving the discrepancy before any tissue is handled.

The bench is full and several large cases are waiting. How do you prioritize?

What they are checking: Managing high volume while keeping turnaround time and quality in balance.

A pathologist disagrees with how you sampled a case. How do you respond?

What they are checking: Taking feedback professionally and learning the pathologist's preferences.

About the work

Walk me through how you gross a complex specimen like a radical prostatectomy or a colectomy for cancer.

What they are checking: Depth of grossing knowledge, including margins, orientation and which sections the pathologist needs.

How do you protect specimen identification from the moment a specimen arrives until the blocks are submitted?

What they are checking: Safeguards against mix-ups, which are among the most serious lab errors.

A frozen section request comes in during surgery. Walk me through what you do and how fast.

What they are checking: Skill with cryostat sections and urgency for intraoperative consults that affect surgery in real time.

What do you include in a gross description so the pathologist can rely on it?

What they are checking: Precise, complete descriptions that support an accurate diagnosis.

How do you handle a specimen with inadequate fixation?

What they are checking: Knowledge of fixation and how it affects downstream testing like biomarkers.

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The full job description

As published by Northwestern Medicine.

The Pathologist Assistant II - PNE reflects the mission, vision, and values of NM, adheres to the organization’s Code of Ethics and Corporate Compliance Program, and complies with all relevant policies, procedures, guidelines and all other regulatory and accreditation standards. In collaboration with the pathologist, the Pathologist Assistant II is responsible for the gross pathology description and sampling of biopsy and/or other selected complex surgical tissue specimens. The dissection sampling and description is performed in accordance with established procedures to aid the pathologist in establishing the diagnosis. The Pathologist Assistant II assists with resident training and provides a variety of activities in support of basic laboratory operations. Responsibilities: • Performs all duties as scheduled by pathologist. • Performs gross examination and dissection of surgical biopsies and large complicated specimens. Maintains specimen integrity and accurate legible specimen identification throughout all technical and clerical processes. Produces high-quality, high-volume work in a timely fashion, always finding better/more efficient ways to do things. • Provides assistance with intra-operative consultations. Cuts, stains, and coverslips cryostat sections for timely review. Documents appropriate turn-around-time tracking information. • Prepares specimens for imaging and photographs specimens. Maintains imaging equipment and files. Organizes radiology files and photography. • Participates in perinatal and adult autopsies as assigned. Reviews autopsy permit and patient charts. Performs related autopsy procedures, reviews gross and microscopic findings with attending, and prepares draft PAD as appropriate. • Assists with orientation and instruction of pathology residents and medical students in Surgical Pathology and Autopsy procedures to include specimen description, dissections, dictation techniques, basic specimen handling, and use of Anatomic Pathology equipment. Provides clinical performance feedback on pathology residents. • Prepares materials and participates in conferences with residents, pathologists, and clinical staff. • Assists in grossing and distributing tissues and organs to approved researchers. Performs technical and clerical tasks related to research projects. RESPONSIBILITIES • Exercises independent judgment in the performance of technical responsibilities. Prioritizes technical workload based on assignment or established priorities, responds effectively to changes in workflow adjusting work to incorporate STAT requests or fluctuations in work volume. • Practices the proficient and safe use of all equipment necessary for the completion of all duties and responsibilities within defined turn-around times. Cleans, disinfects, performs, and documents routine equipment and workspace maintenance per SOP. Reports equipment or instrument malfunctions appropriately. • Assists manager and/or pathologist in development and implementing new and special procedures or techniques. May assist in maintaining procedure manuals in accordance with practice guidelines and requirements of regulatory agencies. • Participates in quality and process improvement efforts. Identifies ways to improve work processes and improve customer satisfaction. Makes recommendations to manager, implements and monitors changes as requested. • Maintains a clean and safe work area. Follows established laboratory safety procedures in accordance with those regulatory bodies such as OSHA, FDA, EPA, etc. Observes and practices Universal Precautions when handling biohazardous material. Assumes a proactive role in laboratory safety and participates in development of safety protocols in surgical pathology. Performs minor spill cleanup per SOP when necessary. • Participates in cost containment initiatives. Responsible for efficient use of supplies and reagents and proper operation of instrumentation. • Provides backup assistance in a variety of activities in support of basic laboratory operations. • Records all documentation consistently and legibly. May create Standard Operating Procedures. Maintains manuals and electronic records for easy retrieval of data as necessary. Investigates, escalates, and documents any discrepancies or unresolved issues appropriately. • Fosters department and laboratory teamwork through effective communication. Adapts to change and handles stressful situations effectively • Takes initiative for personal development by attending teleconferences, educational sessions, and required meetings, etc. • Works off shifts and weekends as needed dependent on workload and department schedule. Required : • Masters of Science • Pathologist Assistant II’s degree, and Pathologist Assistant II Certification (ASCP) or eligible for certification or Illinois licensed MD/DO with current or completed enrollment in anatomical pathology Preferred: • N/A Northwestern Medicine is an equal opportunity employer (disability, VETS) and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, gender identity, veteran status, disability, sexual orientation or any other protected status. Background Check Northwestern Medicine conducts a background check that includes criminal history on newly hired team members and, at times, internal transfers. If you are offered a position with us, you will be required to complete an authorization and disclosure form that gives Northwestern Medicine permission to run the background check. Results are evaluated on a case-by-case basis, and we follow all local, state, and federal laws, including the Illinois Health Care Worker Background Check Act. Artificial Intelligence Disclosure Artificial Intelligence (AI) tools may be used in some portions of the candidate review process for this position, however, all employment decisions will be made by a person. Benefits We offer a wide range of benefits that provide employees with tools and resources to improve their physical, emotional, and financial well-being while providing protection for unexpected life events. Click on or copy and paste URL to your browser to view detailed benefits information NorthwesternMedicine Career Page https://jobs.nm.org/benefits Please refer to the Benefits Eligibility by Employment Classification to determine benefits eligibility for job postings. If sign-on bonus is included in a job posting eligibility is as followed: Internal employees and rehires who left Northwestern Medicine within 1 year are not eligible for the sign-on bonus. Exception : New graduate internal employees seeking their first licensed clinical position as a Registered Nurse at NM may be eligible.

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