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Histotechnician-Full-time Days

Northwestern Medicine · Geneva, IL · Full time · Health Care Provider

Posted Sep 29, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

Tell me about a time you found a specimen problem and had to bring it to a pathologist or resident. How did that go?

What they are checking: Whether they speak up clearly to physicians rather than quietly working around a problem they found.

Our lab uses an occurrence management program. Tell me about a time you reported your own mistake.

What they are checking: Honesty about errors, because a lab that hides near misses cannot fix the process that caused them.

This shift is Monday through Friday, 4 a.m. to 12:30 p.m. What has your experience been with early starts, and how do you stay sharp at that hour?

What they are checking: Whether they have a realistic plan for reliable attendance on a schedule that the whole morning sign-out depends on.

What would you do

You notice a block label does not match the cassette log. What do you do right then, and who do you tell?

What they are checking: Specimen identity discipline, since a labeling error in histology can attach a cancer diagnosis to the wrong patient.

How do you prioritize blocks when you have rush biopsies, routine surgicals and a large backlog all waiting at once?

What they are checking: Whether they understand which cases drive same-day patient decisions and order the work to match.

About the work

Walk me through how you do a cassette-log reconciliation at the start of a 4 a.m. shift, and what you do if the count is off by one.

What they are checking: Whether they treat a missing cassette as a possible lost patient specimen and stop the line until it is found.

A conventional processor throws an alarm halfway through the overnight run. How do you decide what to do with the tissue inside it?

What they are checking: Whether they know the standard alarms well enough to protect the tissue and document the event instead of guessing.

How can you tell at the embedding station that a block was not processed well, and what do you do about it?

What they are checking: Recognizing inadequate processing early, before a pathologist receives a slide that cannot be read.

Tell me how you orient a small skin biopsy compared with a GI biopsy or a tubular structure.

What they are checking: Whether they understand that wrong orientation can hide the very margin or layer the pathologist needs to see.

What is your routine for checking H&E stain quality before slides leave your bench?

What they are checking: Owning slide quality themselves instead of relying on the pathologist to catch weak or uneven staining.

How do you handle formalin and xylene safely, and what would you do about a small spill on the bench?

What they are checking: Chemical safety habits that protect themselves and coworkers in a lab full of fixatives and solvents.

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The full job description

As published by Northwestern Medicine.

This is a full-time, 40 hours per week, 1st shift position located at Delnor Hospital in Geneva. Must be able to work Monday through Friday 4am - 12:30pm. No holidays and No weekends! The Histotechnician reflects the mission, vision, and values of NM, adheres to the organization’s Code of Ethics and Corporate Compliance Program, and complies with all relevant policies, procedures, guidelines and all other regulatory and accreditation standards. The Histotechnician performs routine histology procedures, in accordance with all department specific SOPs and guidelines, resulting in the stained slides for microscopic review and diagnosis by the Pathologist. This position is responsible for communication with pathologists, residents, and coordinators/supervisors regarding specimen problems. The position is also required to participate in the laboratory occurrence management program. RESPONSIBILITIES: • Performs cassette-log reconciliation. Initiates appropriate programs on conventional and microwave tissue processors. Recognizes, resolves, and documents standard processor alarms. • Embeds biopsy, routine surgical, and autopsy tissues, if applicable, per SOP. Recognizes adequacy of processing. • Identifies and orients tissues correctly. Documents tracking and quality issues on embedding log. • Performs and documents routine paraffin block reconciliation. Prioritizes blocks based on established guidelines. • Operates microtome per SOP, and determines appropriate block orientation and alignment, knife angles, and settings to obtain representative sections. • Recognizes acceptable vs. unacceptable sections; evaluates instances in which specific tissue might require a deviation from standard procedures to ensure diagnostic sections are produced. • Appropriate documentation including specimen identification throughout all technical and clerical processes including in the laboratory information system, as well as cassettes, slides and logs, as required by regulatory compliance. • Operates automated instrumentation to stain and coverslip microscopic slides. • Performs manual methods during instrument downtimes. • Recognizes, resolves, and documents unacceptable staining, coverslipping results and/or instrument failure. • Performs special staining techniques using automated instrumentation and manual methods. • Identifies appropriate positive and/or negative controls. Evaluates stains microscopically for acceptable results. • Executes sectioning and staining of frozen tissued. Identifies and corrects staining deficiencies.¿ Documents stains and quality issues. • Performs and/or assists with gross examination, dissection, and selection of representative tissue for microscopic examination for designated specimen, if applicable by site. Resolves discrepancies prior to gross examination and escalates to supervisor or Pathologist when necessary. • Utilizes dictation equipment to document description per procedure, if applicable. • Investigates, escalates, and documents any discrepancies or unresolved issues appropriately. • Prioritizes technical workload based on assignment or established priorities, responds effectively to changes in workflow adjusting work to incorporate STAT requests or fluctuations in work volume. • Exercises independent judgment in the performance of technical responsibilities. • Practices the proficient and safe use of all equipment necessary for the completion of all duties and responsibilities within defined turn-around times. • May perform required Quality System responsibilities including initiating “Quality Investigation Reports”, if needed • Reports equipment or instrument malfunctions appropriately. • Maintains a clean and safe work environment to ensure efficient workflow and compliance with all regulatory requirements. Cleans and disinfects laboratory areas per SOP. Performs minor spill cleanup per SOP when necessary. • Notifies coordinator promptly of any supply issues. • May participate in Safety and Infection Control activities. Follows all required safety procedures, assumes a proactive role in laboratory safety. • Takes initiative for personal development by attending teleconferences, educational sessions, and required meetings, etc. • May participate in the training or teaching of students and staff in the department. Additional functions: • Performs other duties as assigned. • May be asked to assist in specific process improvement projects. • May be asked to assist with problem resolution regarding patient specimens including root cause analysis Required : • Associates degree (if hired after 1/19/2025) with a combination of 12 semester hours (18 quarter hours) in biology and chemistry OR must have successfully completed 60 semester hours (90 quarter hours) of academic credit from an accredited (regionally or nationally) college/university, with a combination of 12 semester hours (18 quarter hours) in biology or chemistry, qualifying the applicant to take the national ASCP certifying exam. Must provide proof of education as stated in CLIA guidelines. • Certification Requirement: Must obtain Histotechnician (HT) ASCP certification within 1 year of hire. • Must meet requirements for performing high complexity testing as defined by federal licensing guidelines (CLIA) and accreditation agencies (TJC,CAP) Preferred : • Associated degree as Histotechnician. Northwestern Medicine is an equal opportunity employer (disability, VETS) and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, gender identity, veteran status, disability, sexual orientation or any other protected status. Background Check Northwestern Medicine conducts a background check that includes criminal history on newly hired team members and, at times, internal transfers. If you are offered a position with us, you will be required to complete an authorization and disclosure form that gives Northwestern Medicine permission to run the background check. Results are evaluated on a case-by-case basis, and we follow all local, state, and federal laws, including the Illinois Health Care Worker Background Check Act. Artificial Intelligence Disclosure Artificial Intelligence (AI) tools may be used in some portions of the candidate review process for this position, however, all employment decisions will be made by a person. Benefits We offer a wide range of benefits that provide employees with tools and resources to improve their physical, emotional, and financial well-being while providing protection for unexpected life events. Click on or copy and paste URL to your browser to view detailed benefits information NorthwesternMedicine Career Page https://jobs.nm.org/benefits Please refer to the Benefits Eligibility by Employment Classification to determine benefits eligibility for job postings. If sign-on bonus is included in a job posting eligibility is as followed: Internal employees and rehires who left Northwestern Medicine within 1 year are not eligible for the sign-on bonus. Exception : New graduate internal employees seeking their first licensed clinical position as a Registered Nurse at NM may be eligible.

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