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Associate Director, Pharmacometrics

AbbVie · North Chicago, IL · Full time · Research

Posted Aug 11, 2026 · We last checked this listing on Oct 6, 2026

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Likely interview questions for this role

Written from this job description, not a generic list. Each one notes what the interviewer is really checking.

About your past

You would ensure timely delivery of regulatory documents and responses to agency comments. Tell me about responding to a regulator's question about your modeling.

What they are checking: Defending modeling to an agency, a specific and revealing experience.

The role asks you to champion innovative approaches across therapeutic areas. Tell me about a method you introduced that other people adopted.

What they are checking: Actual influence rather than personal technical interest.

How do you keep current on modeling and simulation methods and software when the field moves quickly?

What they are checking: Professional habits, named as a duty in the posting.

You may manage personnel including their development and mentoring. What do junior pharmacometricians usually need most?

What they are checking: Depth of experience visible through what they teach.

This asks for a doctorate with five or more years or a master's with eleven or more, in North Chicago, and describes an internally and externally recognized pharmacometrician. How do you maintain an external profile alongside the internal work?

What they are checking: That they read the external recognition expectation and have a plan for it.

What would you do

How do you present a modeling result to a clinical team that wants a simple answer?

What they are checking: Translation, which determines whether pharmacometrics influences decisions.

You represent pharmacometrics in core team meetings. How do you tell a team that the model does not support the dose they want to take forward?

What they are checking: Independence when the answer is unwelcome.

About the work

This role drives pharmacokinetic and pharmacodynamic strategy across multiple major programs. How do you decide what modeling a program actually needs versus what is nice to have?

What they are checking: Strategic restraint, which is what separates a leader from an analyst.

The posting names advanced analytics, machine learning and mechanistic modeling. When is a mechanistic model the right choice over an empirical one?

What they are checking: Method selection reasoning rather than a preference for sophistication.

You are responsible for the appropriateness, quality and accuracy of pharmacometrics deliverables across programs. How do you review someone else's model?

What they are checking: Quality control method on work they did not build.

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The full job description

As published by AbbVie.

The Associate Director, Pharmacometrics will act as an internally and externally recognized pharmacometrician by driving pharmacometrics (PMx) strategy, performing PMx analyses and representing PMx in project teams. They will continuously and consistently develop, implement, and promote innovative PMx methodologies/approaches and provide consultancy and expert advice to other stakeholders. Develop PMx strategy for projects and indications. Responsibilities • Drive Pharmacometrics PK/PD strategy across multiple major projects and programs; collaborate with CPPM senior management in the selection of action plans that best meets business needs in drug development • Responsible for the appropriateness, quality and accuracy of pharmacometrics deliverables • Advise on complex methodologies such as advanced analytics, machine learning and mechanistic modeling • Ensure the timely delivery of PMx regulatory documents and response to regulatory agency comments • Contribute to development of departmental goals; influences strategic PK/PD decisions for the department • Maintain up-to-date knowledge of industry standards in PK/PD data analyses, modeling and simulation methods and software • Represent Pharmacometrics in core team meetings • Champion development, implementation, and promotion of innovative PMx approaches across therapeutic areas; identify and develop process improvement initiatives • Participate in internal and external initiatives/working groups (e.g., cross-functional initiatives, process harmonization, IMI calls, ISoP groups) • May manage personnel including their development, mentoring, and effective delegation • PhD with 5+ year of experience or Master’s degree with 11+ years of experience in a relevant field such as (bio-)statistical modeling and simulation, PKPD modeling, system pharmacology • Strategic thinking and enterprise view • Proven scientific track record and technical skills to perform the role • Demonstrated project management skills such as scope management and progress tracking/driving • Key Leadership Competencies: Understand the business and the cross-functional contributions needed to deliver results; Develops strategic perspective; Connects unrelated concepts, generates original or unique ideas; Influences colleagues to achieve cross-functional alignment; Communicates openly and honestly with all colleagues; Manages conflict and difficult conversations in a constructive and transparent way; Inspires and motivates others and self to high performance AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

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